Is titanium dioxide harmful to the body?

Under the spread of the new crown epidemic, after Americans experienced life and death, they set off the largest "resignation wave" in history, and the number of resignations broke the highest record since statistics began in 2000. Since April this year, more than 4 million people in the United States have voluntarily resigned each month. In August, the number of resignations exceeded 4.27 million, and in November, it rose to 4.4 million. The operation of society is linked. The large number of departures in the United States has led to a large shortage of labor; and the shortage of a large number of labor has directly led to the supply chain crisis in the United States; the supply chain crisis has directly affected prices and prices in the United States. The economy has a direct effect on people's lives.
The economic downturn will affect the market demand for titanium dioxide.

US consumers recently filed a lawsuit against Mars in a California court, claiming that the content of titanium dioxide in Skittles was too high.

According to an indictment filed by US consumers, titanium dioxide can cause changes in DNA in the human body, damage organs such as the brain, and damage the liver and kidneys. The European Food Safety Agency (EFSA) issued a report in May 2021 that, given all available scientific research and data, titanium dioxide is no longer safe as a food additive.

 

What is titanium dioxide?

Titanium dioxide, chemical formula TiO2, as an additive code is 171.

Because of its non-toxic, best opacity, best whiteness and brightness, it has been widely used in many fields, such as paint, plastic, rubber, paper, cosmetics, food, medicine and so on.

 

Titanium dioxide used in pharmaceutical industry

In the pharmaceutical industry, titanium dioxide is often used in pharmaceutical preparations, as a coating agent, colorant and ultraviolet absorbent, for the preparation of coated tablets, pills, granules, capsules and topical preparations.

According to the European Union Trade Association, about 91000 drugs for human use and 800 kinds of veterinary drugs contain titanium dioxide. According to an article published by the European Drug Administration in September 2021 to assess the impact of titanium dioxide on the pharmaceutical industry: it is difficult for the pharmaceutical industry to get rid of titanium dioxide, and this excipient is frequently used in oral solid and semi-solid dosage forms as opaque agents and colorants. such as tablets, capsules, suspensions and so on. It also exists in many essential drugs for human beings, including antibiotics, antidiabetic drugs and so on.

 

Who is to blame?

It is said that the safety problem of titanium dioxide is not titanium dioxide itself, but a certain proportion of nanometer titanium dioxide. Nano-sized particles may be harmful to human health.

 

Can titanium dioxide be replaced?

It is not easy to find a replacement for titanium dioxide.

The European Drug Administration has reported that so far, no single substance has been found to provide a combination of properties unique to TiO2 (such as opacity, enhanced contrast, inertia, UV protection and the resulting product smoothness).

Possible alternatives include calcium carbonate, talc, and starch. However, these alternatives have disadvantages (for example, inability to obtain thin enough film, supply chain problems, and the risk of related element impurities).

 

According to the European Drug Administration, if titanium dioxide is not allowed to add to medicines, it will almost cause a large shortage of drugs and lead to the suspension / withdrawal of these drugs from the EU / European Economic area market. The European Drug Administration's quality working Group (QWP) said there was currently no mechanism for regulators to prioritize products to be reformulated and that the transition period for replacing titanium dioxide would take a decade or more. "each affected pharmaceutical product will require a separate review and evaluation, which will require investigation of alternatives, product reformulation, and collection of new data related to manufacturing, dissolution and stability." The European Drug Administration wrote.

 

Some enterprises have begun to study alternatives to titanium dioxide. for example, the food company ADM has launched a series of white colorant solutions series Pearl Edge, which aims to replace food-grade titanium dioxide, and Caracom, a manufacturer of thin-film coating systems in the pharmaceutical industry, has launched the Newterfield series of full-formula thin-film coating products designed for nutrition, which clearly states that it does not contain titanium dioxide.

 

Titanium dioxide TiO2 powder Price

The price is influenced by many factors including the supply and demand in the market, industry trends, economic activity, market sentiment, and unexpected events.

If you are looking for the latest TiO2 powder price, you can send us your inquiry for a quote. (sales1@rboschco.com)

 

Titanium dioxide TiO2 powder Supplier

RBOSCHCO is a trusted global chemical material supplier&manufacturer with over 12-year-experience in providing super high-quality chemicals and nanomaterials. The company export to many countries including the USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Azerbaijan, Belgium, Cyprus, Czech Republic, Brazil, Chile, Dubai, Japan, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, Germany, France, Italy, Portugal, etc.

As a leading nanotechnology development manufacturer, RBOSCHCO dominates the market. Our professional work team provides perfect solutions to help improve the efficiency of various industries, create value, and easily cope with various challenges.

 

If you are looking for TiO2 powder, please send an email. (sales1@rboschco.com)


According to Reuters, U.S. Treasury officials said they would discuss with G7 leaders pricing caps and tariffs on Russian oil as an alternative to the embargo, which would keep the market supplied, limit price spikes, and reduce Russian revenues.  

The EU foreign ministers' meeting was held in Brussels.  The meeting failed to agree on the sixth round of sanctions, including an oil embargo on Russia, because of objections from Hungary.  

EU High Representative for Foreign Affairs and Security Policy said at a press conference after the meeting, that the meeting failed to reach an agreement on the final adoption of the sixth round of sanctions, the permanent representatives of member states to the EU will continue to discuss. The foreign ministers faced similar difficulties trying to reach an agreement on an oil ban. He said Hungary's position was based on economic rather than political concerns.  

Hungary is highly dependent on Russia for energy, getting more than 60 percent of its oil and 85 percent of its natural gas from Russia.  

A few days ago, the European Commission submitted the sixth round of proposed sanctions against Russia, including a total ban on Russian oil imports by the end of this year. Hungary immediately objected and said it wanted substantial compensation from the EU to offset its loss from giving up Russian oil.

The titanium dioxide price is predicted to increase in the next few days, due to geopolitical factors.

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